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Exposure of healthy volunteers to swine house dust increases formation of leukotrienes, prostaglandin D(2), and bronchial responsiveness to methacholine

BACKGROUND—Acute exposure of healthy subjects to swine house dust causes increased bronchial responsiveness to methacholine but no acute bronchoconstriction. The role of cysteinyl leukotrienes and mast cells in increased bronchial responsiveness is unclear.
METHODS—Ten non-asthmatic subjects were ex...

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Detalhes bibliográficos
Main Authors: O'Sullivan, S., Dahlen, S., Larsson, K., Larsson, B., Malmberg, P., Kumlin, M., Palmberg, L.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745138/
https://ncbi.nlm.nih.gov/pubmed/10195076
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