Effector mechanisms responsible for gamma interferon-mediated host resistance to Legionella pneumophila lung infection: the role of endogenous nitric oxide differs in susceptible and resistant murine hosts.

To facilitate identification of the effector mechanism(s) responsible for gamma interferon (IFN-gamma)-mediated host resistance to Legionella pneumophila, a murine model of legionellosis in BALB/c mice with a targeted disruption in the IFN-gamma gene (gamma knockout [GKO] mice) was developed. Immuno...

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Detalhes bibliográficos
Main Authors: Heath, L, Chrisp, C, Huffnagle, G, LeGendre, M, Osawa, Y, Hurley, M, Engleberg, C, Fantone, J, Brieland, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC174501/
https://ncbi.nlm.nih.gov/pubmed/8945559
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