Effector mechanisms responsible for gamma interferon-mediated host resistance to Legionella pneumophila lung infection: the role of endogenous nitric oxide differs in susceptible and resistant murine hosts.

To facilitate identification of the effector mechanism(s) responsible for gamma interferon (IFN-gamma)-mediated host resistance to Legionella pneumophila, a murine model of legionellosis in BALB/c mice with a targeted disruption in the IFN-gamma gene (gamma knockout [GKO] mice) was developed. Immuno...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Heath, L, Chrisp, C, Huffnagle, G, LeGendre, M, Osawa, Y, Hurley, M, Engleberg, C, Fantone, J, Brieland, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8945559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.12.5151-5160.1996
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