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Recombinant V antigen protects mice against pneumonic and bubonic plague caused by F1-capsule-positive and -negative strains of Yersinia pestis.

The purified recombinant V antigen from Yersinia pestis, expressed in Escherichia coli and adsorbed to aluminum hydroxide, an adjuvant approved for human use, was used to immunize outbred Hsd:ND4 mice subcutaneously. Immunization protected mice from lethal bubonic and pneumonic plague caused by CO92...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Anderson, G W, Leary, S E, Williamson, E D, Titball, R W, Welkos, S L, Worsham, P L, Friedlander, A M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174416/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8890210/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.11.4580-4585.1996
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