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Identification, cloning, and sequencing of the immunoglobulin A1 protease gene of Streptococcus pneumoniae.

The pneumococcus expresses a protease that hydrolyzes human immunoglobulin A1 (IgA1). A gene for IgA1 protease was identified from a plasmid library of pneumococcal DNA because of the effect of its overexpression on the colony morphology of Streptococcus pneumoniae. The deduced 1,964-amino-acid sequ...

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Udgivet i:Infect Immun
Principais autores: Wani, J H, Gilbert, J V, Plaut, A G, Weiser, J N
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174324/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8926056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.10.3967-3974.1996
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