Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B.

There is increasing evidence that lipoproteins of Treponema pallidum and Borrelia burgdorferi are key inflammatory mediators during syphilis and Lyme disease. A principal objective of the present study was to identify more precisely similarities and divergences among lipopolysaccharide (LPS)- and li...

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Détails bibliographiques

Publié dans:	Infect Immun
Auteurs principaux:	Norgard, M V, Arndt, L L, Akins, D R, Curetty, L L, Harrich, D A, Radolf, J D
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8751937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.9.3845-3852.1996
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