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Immunization of Aotus nancymai with recombinant C terminus of Plasmodium falciparum merozoite surface protein 1 in liposomes and alum adjuvant does not induce protection against a challenge infection.

Merozoite surface protein 1 (MSP-1) of Plasmodium falciparum is an antimalarial vaccine candidate. The highly conserved 19-kDa C-terminal processing fragment of MSP-1 (MSP-1(19)) is of particular interest since it contains epitopes recognized by monoclonal antibodies which inhibit the invasion of er...

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Detalhes bibliográficos
Main Authors: Burghaus, P A, Wellde, B T, Hall, T, Richards, R L, Egan, A F, Riley, E M, Ballou, W R, Holder, A A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC174271/
https://ncbi.nlm.nih.gov/pubmed/8751907
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