cis Elements and trans factors are both important in strain-specific regulation of the leukotoxin gene in Actinobacillus actinomycetemcomitans.

Actinobacillus actinomycetemcomitans, the etiologic agent of localized juvenile periodontitis, produces a potent leukotoxin that kills human neutrophils. The production of leukotoxin RNA can vary more than 50-fold among isolates of A. actinomycetemcomitans, and strains expressing high levels of leuk...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Kolodrubetz, D, Spitznagel, J, Wang, B, Phillips, L H, Jacobs, C, Kraig, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8751884/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.9.3451-3460.1996
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