cis Elements and trans factors are both important in strain-specific regulation of the leukotoxin gene in Actinobacillus actinomycetemcomitans.

Actinobacillus actinomycetemcomitans, the etiologic agent of localized juvenile periodontitis, produces a potent leukotoxin that kills human neutrophils. The production of leukotoxin RNA can vary more than 50-fold among isolates of A. actinomycetemcomitans, and strains expressing high levels of leuk...

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Bibliographic Details
Main Authors: Kolodrubetz, D, Spitznagel, J, Wang, B, Phillips, L H, Jacobs, C, Kraig, E
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC174248/
https://ncbi.nlm.nih.gov/pubmed/8751884
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