Brucella abortus as a potential vaccine candidate: induction of interleukin-12 secretion and enhanced B7.1 and B7.2 and intercellular adhesion molecule 1 surface expression in elutriated human monocytes stimulated by heat-inactivated B. abortus.

Development of a vaccine which is capable of generating a strong cellular immune response associated with gamma interferon (IFN-gamma) production and cytotoxic T-cell development requires that the immunogen be capable of inducing the secretion of interleukin-12 (IL-12), which is a pivotal factor for...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Zaitseva, M, Golding, H, Manischewitz, J, Webb, D, Golding, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174195/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8757841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.8.3109-3117.1996
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