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Mitogenic activities of amino acid substitution mutants of staphylococcal enterotoxin B in human and mouse lymphocyte cultures.

Site-directed mutagenesis has been used to introduce amino acid substitutions at specific residues of the staphylococcal enterotoxin B (SEB) gene cloned from Staphylococcus aureus 10-275. The mitogenic activities of these derivatives were determined in two assay systems: (i) mouse spleen cells and (...

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Bibliographic Details
Main Authors: Neill, R J, Jett, M, Crane, R, Wootres, J, Welch, C, Hoover, D, Gemski, P
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC174181/
https://ncbi.nlm.nih.gov/pubmed/8757827
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