Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC.

Outbred mice were immunized with the soluble fraction of a crude Escherichia coli lysate containing either recombinant outer surface protein C (OspC or P39 of Borrelia burgdorferi B31 (low passage). Following seroconversion, the mice were challenged with an infectious dose of B. burgdorferi B31 via...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Gilmore, R D, Kappel, K J, Dolan, M C, Burkot, T R, Johnson, B J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675332/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.6.2234-2239.1996
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