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A cloned major Schistosoma mansoni egg antigen with homologies to small heat shock proteins elicits Th1 responsiveness.

In schistosomiasis mansoni, soluble egg antigens of the worm induce chronic T-cell-mediated granulomatous tissue responses. Since the first preparation of crude soluble egg antigen extract, a dearth of highly purified antigens has hampered the identification of granuloma inducer molecules. Here we r...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Cai, Y, Langley, J G, Smith, D I, Boros, D L
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8613387/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.5.1750-1755.1996
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