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Mitotic block and delayed lethality in HeLa epithelial cells exposed to Escherichia coli BM2-1 producing cytotoxic necrotizing factor type 1.

The cytopathic effect (CPE) of Escherichia coli producing cytotoxic necrotizing factor type 1 (CNF1) was investigated by using a human epithelial cell (HeLa) model of infection with CNF1-producing E. coli BM2-1. This strain was shown to bind loosely, but massively, to HeLa cells. A 4-h interaction b...

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Published in:Infect Immun
Main Authors: De Rycke, J, Mazars, P, Nougayrede, J P, Tasca, C, Boury, M, Herault, F, Valette, A, Oswald, E
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173981/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8613380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.5.1694-1705.1996
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