Association of a polymorphism of the transforming growth factor-ß1 gene with cerebral amyloid angiopathy

Background: A recent study showed that transforming growth factor-ß1 (TGF-ß1) induces amyloid-ß deposition in cerebral blood vessels and meninges of a transgenic mouse model of Alzheimer's disease (AD), and that TGF-ß1 mRNA levels are correlated with cerebral amyloid angiopathy (CAA) in human A...

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Main Authors: Hamaguchi, T, Okino, S, Sodeyama, N, Itoh, Y, Takahashi, A, Otomo, E, Matsushita, M, Mizusawa, H, Yamada, M
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2005
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Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1739647/
https://ncbi.nlm.nih.gov/pubmed/15834029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2003.034454
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