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Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha.

Peptides with potent broad-spectrum antibiotic activity have been identified in many animal species. Recent investigations have demonstrated that epithelial cells are a site of antibiotic peptide expression, suggesting that these peptides contribute to host defense at mucosal surfaces. Expression of...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Russell, J P, Diamond, G, Tarver, A P, Scanlin, T F, Bevins, C L
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8613361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.5.1565-1568.1996
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