Randomized, double-blind placebo-controlled trial to evaluate the safety and immunogenicity of combined Salmonella typhi Ty21a and Vibrio cholerae CVD 103-HgR live oral vaccines.

Healthy adults (n=330) were randomized to receive either a bivalent vaccine composed of Vibrio cholerae CVD 103-HgR and Salmonella typhi Ty21a or a placebo. The combined vaccine was well tolerated. Approximately 80% of vaccines manifested a significant rise in anti-S. typhi immunoglobulin G or immun...

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Détails bibliographiques

Publié dans:	Infect Immun
Auteurs principaux:	Kollaritsch, H, Furer, E, Herzog, C, Wiedermann, G, Que, J U, Cryz, S J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173943/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8606118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.4.1454-1457.1996
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