Cell response to oxidative stress induced apoptosis in patients with Leber's hereditary optic neuropathy

Objectives: Leber's hereditary optic neuropathy (LHON) is a maternally inherited disease in which acute or subacute bilateral visual loss occurs preferentially in young men. Over 95% of LHON cases are associated with one of three mitochondrial DNA (mtDNA) point mutations, but only 50% of men an...

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Detalhes bibliográficos
Main Authors: Battisti, C, Formichi, P, Cardaioli, E, Bianchi, S, Mangiavacchi, P, Tripodi, S, Tosi, P, Federico, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2004
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Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1738830/
https://ncbi.nlm.nih.gov/pubmed/15548492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2003.024372
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