Identification of T-cell determinants in natural immune responses to the Plasmodium falciparum apical membrane antigen (AMA-1) in an adult population exposed to malaria.

AMA-1 of Plasmodium falciparum is a promising candidate antigen in malaria vaccine development. In this study, we have mapped the immunodominant T-cell determinants in this antigen by using synthetic peptides. From the amphipathic scores, 17 putative T-cell determinants were identified. Nine of the...

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Autors principals: Lal, A A, Hughes, M A, Oliveira, D A, Nelson, C, Bloland, P B, Oloo, A J, Hawley, W E, Hightower, A W, Nahlen, B L, Udhayakumar, V
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC173881/
https://ncbi.nlm.nih.gov/pubmed/8641760
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