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Lack of cleavage of IcsA in Shigella flexneri causes aberrant movement and allows demonstration of a cross-reactive eukaryotic protein.

Once in the cytoplasm of mammalian cells, Shigella flexneri expresses a motile phenotype caused by polar directional assembly of actin. This process depends on accumulation of IcsA (VirG), a 120-kDa protein with ATPase activity, at the pole of the bacterium opposite to that at which ongoing septatio...

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Bibliográfalaš dieđut
Publikašuvnnas:Infect Immun
Váldodahkkit: d'Hauteville, H, Dufourcq Lagelouse, R, Nato, F, Sansonetti, P J
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology (ASM) 1996
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173794/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8550200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.2.511-517.1996
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