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Neurophysiological modulation of the subthalamic nucleus by pallidal stimulation in Parkinson's disease

Objectives: Current models of basal ganglia dysfunction in Parkinson's disease suggest a pivotal role of subthalamic nucleus (STN) hyperactivity. There is a direct excitatory output to the globus pallidus internus (GPi), which in turn hyperinhibits the motor thalamus and leads to a lack of cort...

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Hlavní autoři: Sterio, D, Rezai, A, Mogilner, A, Zonenshayn, M, Gracies, J, Kathirithamby, K, Beric, A
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1737769/
https://ncbi.nlm.nih.gov/pubmed/11861688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.72.3.325
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