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Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations

OBJECTIVES—Cerebral cavernous malformations are linked to mutations of the KRIT1 gene at the CCM1 locus and to mutations at two other loci, CCM2 and CCM3, for which genes are not yet identified. There is little information regarding the function of KRIT1. Histological and immunocytochemical analysis...

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Bibliografische gegevens
Hoofdauteurs: Clatterbuck, R, Eberhart, C, Crain, B, Rigamonti, D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Group 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1737494/
https://ncbi.nlm.nih.gov/pubmed/11459890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.71.2.188
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