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Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection.

We sought to identify which Pseudomonas aeruginosa products are involved initiating respiratory tract infection. Defined mutants derived from strain PAO i.e., PAOR1 (lasR),PAO-pmm (algC) (an LPS mutant), and AK1152 (which is Fla- and lacks functional pili), were significantly less virulent than PAO1...

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Bibliographic Details
Main Authors: Tang, H B, DiMango, E, Bryan, R, Gambello, M, Iglewski, B H, Goldberg, J B, Prince, A
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC173724/
https://ncbi.nlm.nih.gov/pubmed/8557368
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