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Family history and DNA analysis in patients with suspected Huntington's disease

OBJECTIVES—Until recently a definite diagnosis of Huntington's disease could be made by a combination of clinical findings, a positive family history, and pathological confirmation. Prevalence data are based on these criteria. After finding the gene and its pathogenic mutation direct diagnostic...

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Main Authors: Siesling, S, de Vlis, M V.-v., Losekoot, M, Belfroid, R, Maat-Kievit, J, Kremer, H, Roos, R
格式: Artigo
語言:Inglês
出版: BMJ Group 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1737014/
https://ncbi.nlm.nih.gov/pubmed/10864604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.69.1.54
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