Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages.

Cell invasion by Trypanosoma cruzi and its intracellular replication are essential for continuation of the parasite life cycle and for production of Chagas' disease. T. cruzi is able to replicate in nucleated cells and can be killed by activated macrophages. Gamma interferon (IFN-gamma) is one of th...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Silva, J S, Vespa, G N, Cardoso, M A, Aliberti, J C, Cunha, F Q
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173696/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.12.4862-4867.1995
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