Angiotensin converting enzyme and endothelial nitric oxide synthase DNA polymorphisms and late onset Alzheimer's disease

OBJECTIVES—Several lines of evidence suggest that the endothelial constitutive nitric oxide synthase (ecNOS) and angiotensin converting enzyme (ACE) may have a role in Alzheimer's disease. ACE is widely expressed in the brain, and a DNA polymorphism at the ACE gene has been linked to the risk f...

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Main Authors: Alvarez, R., Alvarez, V., Lahoz, C., Martinez, C., Pena, J., Sanchez, J., Guisasola, L., Salas-Puig, J., Moris, G., Vidal, J., Ribacoba, R., Menes, B., Uria, D., Coto, E.
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 1999
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736659/
https://ncbi.nlm.nih.gov/pubmed/10567488
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