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Trypanosoma cruzi immunosuppressive factor decreases the interleukin-2 mRNA level in cultured normal activated human lymphocytes.

We show here that the marked inhibition of interleukin-2 production seen in hosts acutely infected with Trypanosoma cruzi can be reproduced in vitro by adding a T. cruzi suspension filtrate to cultures of activated human peripheral blood mononuclear cells. This effect was not due to an accelerated d...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Majumder, S, Kierszenbaum, F
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591102/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.11.4546-4549.1995
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