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Borrelia burgdorferi upregulates expression of adhesion molecules on endothelial cells and promotes transendothelial migration of neutrophils in vitro.

The accumulation of leukocytic infiltrates in perivascular tissues is a key step in the pathogenesis of Lyme disease, a chronic inflammatory disorder caused by Borrelia burgdorferi. During an inflammatory response, endothelial cell adhesion molecules mediate the attachment of circulating leukocytes...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Sellati, T J, Burns, M J, Ficazzola, M A, Furie, M B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591083/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.11.4439-4447.1995
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