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GTP cyclohydrolase deficiency; intrafamilial variation in clinical phenotype, including levodopa responsiveness

A family with a dominant form of partial GTP cyclohydrolase deficiency is described. Clinical severity varied from mild involvement with complete responsiveness to levodopa to severe dystonia precluding any voluntary activity including talking, progressive contractures, and only partial responsivene...

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Detalhes bibliográficos
Main Authors: Robinson, R., McCarthy, G., Bandmann, O., Dobbie, M., Surtees, R., Wood, N.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736164/
https://ncbi.nlm.nih.gov/pubmed/9886460
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