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Pseudoxanthoma elasticum: a clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations

Pseudoxanthoma elasticum (PXE) is an inherited systemic disease of connective tissue primarily affecting the skin, retina, and cardiovascular system. It is characterised pathologically by elastic fibre mineralisation and fragmentation (so called "elastorrhexia"), and clinically by high het...

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Detalhes bibliográficos
Main Authors: Chassaing, N, Martin, L, Calvas, P, Le Bert, M, Hovnanian, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735972/
https://ncbi.nlm.nih.gov/pubmed/15894595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.030171
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