The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts

Background: In both familial and sporadic atypical haemolytic-uraemic syndrome (aHUS), mutations have been reported in regulators of the alternative complement pathway including factor H (CFH), membrane cofactor protein (MCP), and the serine protease factor I (IF). A characteristic feature of both M...

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Autori principali: Fremeaux-Bacchi, V, Kemp, E, Goodship, J, Dragon-Durey, M, Strain, L, Loirat, C, Deng, H, Goodship, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2005
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735946/
https://ncbi.nlm.nih.gov/pubmed/15784724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.030783
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