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Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults

Background: Several studies have shown linkage of chromosome 12q 13–24 with atopy related phenotypes. Among candidate genes in this region is STAT6 (signal transducer and activator of transcription), which is essential for Th2 cell differentiation, recruitment, and effector function. Methods: We eva...

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Autores principales: Weidinger, S, Klopp, N, Wagenpfeil, S, Rummler, L, Schedel, M, Kabesch, M, Schafer, T, Darsow, U, Jakob, T, Behrendt, H, Wichmann, H, Ring, J, Illig, T
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735893/
https://ncbi.nlm.nih.gov/pubmed/15342695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.020263
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