BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing

Background: According to the international criteria for hereditary non-polyposis colorectal cancer (HNPCC) diagnostics, cancer patients with a family history or early onset of colorectal tumours showing high microsatellite instability (MSI-H) should receive genetic counselling and be offered testing...

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Autors principals: Domingo, E, Laiho, P, Ollikainen, M, Pinto, M, Wang, L, French, A, Westra, J, Frebourg, T, Espin, E, Armengol, M, Hamelin, R, Yamamoto, H, Hofstra, R, Seruca, R, Lindblom, A, Peltomaki, P, Thibodeau, S, Aaltonen, L, Schwartz, S
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2004
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735885/
https://ncbi.nlm.nih.gov/pubmed/15342696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.020651
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