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Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease

Background: There is evidence that iron may play a role in the pathology of Alzheimer's disease (AD). There may be genetic factors that contribute to iron deposition resulting in tissue damage thus exacerbating AD. Methods: We have genotyped 269 healthy elderly controls, 191 cases with definite...

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Autori principali: Robson, K, Lehmann, D, Wimhurst, V, Livesey, K, Combrinck, M, Merryweather-Clar..., A, Warden, D, Smith, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735734/
https://ncbi.nlm.nih.gov/pubmed/15060098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2003.015552
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