Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells.

The adenylate cyclase (AC) toxin (CyaA) of Bordetella pertussis has an invasive catalytic domain (AC domain) which penetrates the cytoplasmic membrane of a variety of eukaryotic cells and intoxicates them by unregulated synthesis of cyclic AMP. Previous work led to identification of five permissive...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Sebo, P, Fayolle, C, d'Andria, O, Ladant, D, Leclerc, C, Ullmann, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173542/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7558291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.10.3851-3857.1995
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