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Differential antibody isotype reactivity to specific antigens in human lymphatic filariasis: gp15/400 preferentially induces immunoglobulin E (IgE), IgG4, and IgG2.

Lymphatic filarial infection in humans is associated with a strong skewing of the immune response towards the TH2 arm, with prominent interleukin 4-producing cells and elevated levels of immunoglobulin G4 (IgG4) and IgE antibodies in peripheral blood. To determine how such a generalized TH2 imbalanc...

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Main Authors: Yazdanbakhsh, M, Paxton, W A, Brandenburg, A, Van Ree, R, Lens, M, Partono, F, Maizels, R M, Selkirk, M E
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC173530/
https://ncbi.nlm.nih.gov/pubmed/7558279
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