Differential antibody isotype reactivity to specific antigens in human lymphatic filariasis: gp15/400 preferentially induces immunoglobulin E (IgE), IgG4, and IgG2.

Lymphatic filarial infection in humans is associated with a strong skewing of the immune response towards the TH2 arm, with prominent interleukin 4-producing cells and elevated levels of immunoglobulin G4 (IgG4) and IgE antibodies in peripheral blood. To determine how such a generalized TH2 imbalanc...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Yazdanbakhsh, M, Paxton, W A, Brandenburg, A, Van Ree, R, Lens, M, Partono, F, Maizels, R M, Selkirk, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7558279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.10.3772-3779.1995
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