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Breakpoint analysis of Turner patients with partial Xp deletions: implications for the lymphoedema gene location

BACKGROUND—Turner syndrome is characterised by a 45,X karyotype and a variety of skeletal, lymphoedemic, and gonadal anomalies. Genes involved in the Turner phenotype are thought to be X/Y homologous with the X genes escaping X inactivation. Haploinsufficiency of the SHOX gene has been reported to c...

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Main Authors: Boucher, C., Sargent, C., Ogata, T., Affara, N.
格式: Artigo
語言:Inglês
出版: BMJ Group 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734929/
https://ncbi.nlm.nih.gov/pubmed/11546827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.38.9.591
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