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A novel germline mutation of the PTEN gene in a patient with macrocephaly, ventricular dilatation, and features of VATER association

Mutations of the PTEN gene are associated with hamartoma-neoplasia syndromes. While germline mutations at this chromosome 10q22-23 locus have been observed in patients with Cowden syndrome (CS) and Bannayan-Riley-Ruvalcaba syndrome (BRR), both of which phenotypes are associated with hamartomata and...

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Detalhes bibliográficos
Main Authors: Reardon, W., Zhou, X., Eng, C.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734782/
https://ncbi.nlm.nih.gov/pubmed/11748304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.38.12.820
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