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The ACE gene and Alzheimer's disease susceptibility

A recent study suggested that the insertion (I) allele in intron 16 of the angiotensin converting enzyme gene (ACE) is associated with Alzheimer's disease (AD) risk. In our series of 239 necropsy confirmed late onset AD cases and 342 elderly non-demented controls aged >73 years, we found sig...

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Bibliografiske detaljer
Main Authors: Narain, Y., Yip, A., Murphy, T., Brayne, C., Easton, D., Evans, J. G., Xuereb, J., Cairns, N., Esiri, M., Furlong, R., Rubinsztein, D.
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734696/
https://ncbi.nlm.nih.gov/pubmed/10978362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.37.9.695
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