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A microdeletion in 19q13.2 associated with mental retardation, skeletal malformations, and Diamond-Blackfan anaemia suggests a novel contiguous gene syndrome

Diamond-Blackfan anaemia (DBA) is a constitutional red blood cell hypoplasia which may be associated with a variety of developmental abnormalities. A gene for DBA was recently mapped to chromosome 19q13.2 and subsequently cloned. Analysis of 19q marker alleles in DNA of sporadic DBA cases showed de...

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Главные авторы: Tentler, D., Gustavsson, P., Elinder, G., Eklof, O., Gordon, L., Mandel, A., Dahl, N.
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Group 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734524/
https://ncbi.nlm.nih.gov/pubmed/10662814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.37.2.128
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