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Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis

Multiple endocrine neoplasia type 2 (MEN 2) is an inherited cancer syndrome characterised by medullary thyroid carcinoma (MTC), with or without phaeochromocytoma and hyperparathyroidism. MEN 2 is unusual among cancer syndromes as it is caused by activation of a cellular oncogene, RET. Germline mutat...

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Detalles Bibliográficos
Main Authors: Hansford, J., Mulligan, L.
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2000
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734482/
https://ncbi.nlm.nih.gov/pubmed/11073534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.37.11.817
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