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Genetic analysis of the 3' untranslated region of the tumour necrosis factor shows a highly conserved region in rheumatoid arthritis affected and unaffected subjects

Tumour necrosis factor (TNF) is a key proinflammatory mediator in rheumatoid arthritis (RA). The TNF locus, situated in the class III region of the MHC, is flanked by five microsatellite markers. It has previously been shown that this region influences susceptibility to RA; two TNF microsatellite ha...

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Autors principals: Waldron-Lynch, F, Adams, C, Shanahan, F, Molloy, M, O'Gara, F
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734333/
https://ncbi.nlm.nih.gov/pubmed/10204847
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