Mendelian segregation of normal CAG trinucleotide repeat alleles at three autosomal loci

Segregation ratio distortion (SRD) with preferential transmission of expanded CAG alleles has been reported in Machado-Joseph disease (MJD/SCA3), spinocerebellar ataxia type I (SCA1), and dentatorubral-pallidoluysian atrophy (DRPLA). We have examined the transmission frequencies of alleles in normal...

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Hlavní autoři: MacMillan, J, Voisey, J, Healey, S, Martin, N
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 1999
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734316/
https://ncbi.nlm.nih.gov/pubmed/10204858
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