A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors

Melanocortin-4 receptor (Mc4r)-null mice exhibit late-onset obesity. To determine whether aberrant metabolism contributes to the obesity, food consumption by Mc4r-null mice was restricted to (pair-fed to) that consumed by wild-type (WT) mice. Pair-fed Mc4r-null females maintained body weights interm...

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Main Authors: Ste. Marie, Linda, Miura, Grant I., Marsh, Donald J., Yagaloff, Keith, Palmiter, Richard D.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC17343/
https://ncbi.nlm.nih.gov/pubmed/11027312
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