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A conserved mechanism of retrovirus restriction in mammals

The murine Fv1 gene restricts infection by N- or B-tropic murine leukemia viruses at a postentry, preintegration stage. The Fv1-sensitive viruses previously used for the study of Fv1 encode an ecotropic envelope gene and thus only infect rodent cells. Consequently, the study of Fv1 restriction has b...

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Detalhes bibliográficos
Main Authors: Towers, Greg, Bock, Michael, Martin, Samia, Takeuchi, Yasuhiro, Stoye, Jonathan P., Danos, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17335/
https://ncbi.nlm.nih.gov/pubmed/11027299
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