Functional expression of falcipain, a Plasmodium falciparum cysteine proteinase, supports its role as a malarial hemoglobinase.

Erythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously shown that a Plasmodium falciparum trophozoite cysteine proteinase, now termed falcipain, is required for hemoglobin degradation, and we have hypothesized that th...

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Détails bibliographiques

Publié dans:	Infect Immun
Auteurs principaux:	Salas, F, Fichmann, J, Lee, G K, Scott, M D, Rosenthal, P J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7768590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.6.2120-2125.1995
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