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Fas ligand upregulation is an early event in colonic carcinogenesis

Background/Aims—Fas ligand (FasL) is a mediator of apoptosis via the Fas receptor (Fas/CD95/APO-1). Normal colonic epithelium expresses Fas, and appears to be relatively sensitive to Fas mediated apoptosis. Colonic adenocarcinomas coexpress FasL and Fas without undergoing widespread apoptosis. This...

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Bibliografiske detaljer
Main Authors: Bennett, M, O'Connell, J, Houston, A, Kelly, J, O'Sullivan, G, Collins, J, Shanahan, F
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1731496/
https://ncbi.nlm.nih.gov/pubmed/11477113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.54.8.598
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