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Fas ligand upregulation is an early event in colonic carcinogenesis
Background/Aims—Fas ligand (FasL) is a mediator of apoptosis via the Fas receptor (Fas/CD95/APO-1). Normal colonic epithelium expresses Fas, and appears to be relatively sensitive to Fas mediated apoptosis. Colonic adenocarcinomas coexpress FasL and Fas without undergoing widespread apoptosis. This...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1731496/ https://ncbi.nlm.nih.gov/pubmed/11477113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.54.8.598 |
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