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Predictive value of topoisomerase IIα immunostaining in urothelial bladder carcinoma

Aims—The nuclear enzyme DNA topoisomerase II has been shown to be required for chromatin condensation and chromosomal segregation during mitosis; its isoform topo IIα is linked with active cell proliferation in mammalian cells. The aim of this study was to examine the relation of the expression of t...

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Detalhes bibliográficos
Main Authors: Nakopoulou, L, Zervas, A, Lazaris, A, Constantinides, C, Stravodimos, C, Davaris, P, Dimopoulos, C
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1731402/
https://ncbi.nlm.nih.gov/pubmed/11304849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.54.4.309
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