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Globotriaosylceramide, Gb3, is an alternative functional receptor for Shiga-like toxin 2e.

We reexamined the binding specificity of the Shiga-like toxin variant associated with porcine edema disease, SLT2e, which is reported to be more cytotoxic for Vero cells than for HeLa cells, by using receptor-deficient cells and a liposomal insertion system for purified glycolipids. We found that SL...

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Autors principals: Keusch, G T, Jacewicz, M, Acheson, D W, Donohue-Rolfe, A, Kane, A V, McCluer, R H
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC173124/
https://ncbi.nlm.nih.gov/pubmed/7868240
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