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Secretion of human interleukin 2 by recombinant Mycobacterium bovis BCG.

The human interleukin 2 (huIL-2) gene was introduced into Mycobacterium bovis BCG by using the integrative vector pMV306. To express and secrete huIL-2 from BCG, two different plasmids, CI and CII, were made. In CI, the huIL-2-encoding region was under the control of the alpha-antigen promoter of BC...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Kong, D, Kunimoto, D Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7868249/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.3.799-803.1995
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