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Secretion of human interleukin 2 by recombinant Mycobacterium bovis BCG.

The human interleukin 2 (huIL-2) gene was introduced into Mycobacterium bovis BCG by using the integrative vector pMV306. To express and secrete huIL-2 from BCG, two different plasmids, CI and CII, were made. In CI, the huIL-2-encoding region was under the control of the alpha-antigen promoter of BC...

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Autors principals: Kong, D, Kunimoto, D Y
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC173073/
https://ncbi.nlm.nih.gov/pubmed/7868249
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