Monophosphoryl lipid A behaves as a T-cell-independent type 1 carrier for hapten-specific antibody responses in mice.

It is known that the lipopolysaccharide (LPS) of gram-negative bacteria, in addition to being a potent adjuvant, is an effective carrier for covalently associated haptens. However, the toxic nature of most forms of LPS precludes their use as adjuvants or carriers for human vaccines. 4'-Monophosphory...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Myers, K R, Beining, P, Betts, M, Snippe, H, Inman, J, Golding, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172974/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7806354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.1.168-174.1995
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