Heat stress alters the virulence of a rifampin-resistant mutant of Francisella tularensis LVS.
We have studied the stress response of a rifampin-resistant mutant of Francisella tularensis LVS. This mutant, Rif 7, was avirulent with an intraperitoneally administered 50% lethal dose greater than 10(7) CFU in a murine model of infection. Exposure of Rif 7 to heat stress for 5 h in vitro resulted...
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| Veröffentlicht in: | Infect Immun |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1995
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172972/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7806352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.1.154-159.1995 |
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